Affordable Access

The bovine genes for phosphoglycerate kinase, glucose-6-phosphate dehydrogenase, alpha-galactosidase, and hypoxanthine phosphoribosyltransferase are linked to the X chromosome in cattle-mouse cell hybrids.

Authors
  • Shimizu, N
  • Shimizu, Y
  • Kondo, I
  • Woods, C
  • Wegner, T
Type
Published Article
Journal
Cytogenetics and cell genetics
Publication Date
Jan 01, 1981
Volume
29
Issue
1
Pages
26–31
Identifiers
PMID: 6257451
Source
Medline
License
Unknown

Abstract

Bovine embryonic trachea cells were hybridized with mouse A9 cells deficient in hypoxanthine phosphoribosyltransferase, and cattle-mouse hybrid cells clones were isolated after HAT/ouabain selection. In these interspecific cell hybrids, bovine glucose-6-phosphate dehydrogenase, alpha-galactosidase, and phosphoglycerate kinase were expressed concordantly with bovine HPRT. Their expression depended on the presence of bovine X chromosome. These data indicated that the genes for G6PD, PGK, and HPRT are linked and can be assigned to the bovine X chromosome.

Report this publication

Statistics

Seen <100 times