The bovine genes for phosphoglycerate kinase, glucose-6-phosphate dehydrogenase, alpha-galactosidase, and hypoxanthine phosphoribosyltransferase are linked to the X chromosome in cattle-mouse cell hybrids.
Bovine embryonic trachea cells were hybridized with mouse A9 cells deficient in hypoxanthine phosphoribosyltransferase, and cattle-mouse hybrid cells clones were isolated after HAT/ouabain selection. In these interspecific cell hybrids, bovine glucose-6-phosphate dehydrogenase, alpha-galactosidase, and phosphoglycerate kinase were expressed concordantly with bovine HPRT. Their expression depended on the presence of bovine X chromosome. These data indicated that the genes for G6PD, PGK, and HPRT are linked and can be assigned to the bovine X chromosome.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 07/01/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6257451