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Botanical description, phytochemistry, traditional uses, and pharmacology of Crataeva nurvala Buch. Ham.: an updated review

Authors
  • Kumar, Dinesh1, 2
  • Sharma, Shivangi1
  • Kumar, Sunil1
  • 1 Kurukshetra University, Kurukshetra, Haryana, 136119, India , Kurukshetra (India)
  • 2 Ben-Gurion University of the Negev, Beer Sheva, 84105, Israel , Beer Sheva (Israel)
Type
Published Article
Journal
Future Journal of Pharmaceutical Sciences
Publisher
Springer Berlin Heidelberg
Publication Date
Dec 02, 2020
Volume
6
Issue
1
Identifiers
DOI: 10.1186/s43094-020-00106-1
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundCrataeva nurvala Buch. Ham., an important medicinal plant of the Capparidaceae family, is widely distributed in India and tropical and subtropical parts of the world. It has been reported for its folkloric use in various disorders such as blood purifier, breathing problems, fever, metabolic disorders, wound healing, memory loss, and weak immune system.ResultsThe present review has focused on the botanical description and ethnomedicinal and traditional uses of C. nurvala along with its reported pharmacological activities. Chief chemical constituents and pharmacological aspects of C. nurvala have been deeply explored to unravel the unexplored folklore/ethnomedicinal uses of this plant so that the researchers working on this plant may be able to find new insights to continue further investigation on this plant. The pharmacological aspects like anti-diabetic, anti-inflammatory, anti-nociceptive, anti-diarrheal, anti-fertility, anti-pyretic, and anti-cancer potentials evaluated by various in vitro/in vivo methods on this plant have been reported.ConclusionVarious traditional uses have been reported that need to be scientifically investigated in depth and several pharmacological activities have been reported for the C. nurvala, but more detailed and mechanism-based studies linked to a particular lead compound need to be targeted in the future. Moreover, this plant has not been completely assessed on the basis of its safety and efficacy on humans. It is expected that this review will compile and improve the existing knowledge on the potential utilization of C. nurvala in complementary and alternative medicine.

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