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Bone metabolism and mineral density in patients with beta-thalassemia major.

Authors
  • Dundar, Umit
  • Kupesiz, Alphan
  • Ozdem, Sebahat
  • Gilgil, Erdal
  • Tuncer, Tiraje
  • Yesilipek, Akif
  • Gultekin, Meral
Type
Published Article
Journal
Saudi medical journal
Publication Date
Sep 01, 2007
Volume
28
Issue
9
Pages
1425–1429
Identifiers
PMID: 17768474
Source
Medline
License
Unknown

Abstract

The BMD is decreased in thalassemic patients. Growth retardation, growth hormone / IGF-I / IGFBP-3 axis dysfunction, gonadal dysfunction and hypothalomo-pituitary-gonadal axis dysfunction may be responsible for the development of osteoporosis in the patients with beta-thalassemia major.

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