Affordable Access

Bone mass regulation of leptin and postmenopausal osteoporosis with obesity.

Authors
  • Legiran, Siswo
  • Brandi, Maria Luisa
Type
Published Article
Journal
Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
Publication Date
Sep 01, 2012
Volume
9
Issue
3
Pages
145–149
Identifiers
PMID: 23289027
Source
Medline
Keywords
License
Unknown

Abstract

There are similarities in the mechanism between estrogen and leptin in influencing the process of bone remodeling. It may be considered that the role of estrogen can be replaced by leptin. Molecular genetic aspects that play a role in bone remodeling, such as leptin, leptin receptors, cytokines (e.g. RANK, RANKL, and OPG), require further study to be useful, especially regarding osteoporosis therapy based on genetic analysis.

Report this publication

Statistics

Seen <100 times