Affordable Access

Bone mass in ankylosing spondylitis.

Authors
  • Reid, D M
  • Nicoll, J J
  • Kennedy, N S
  • Smith, M A
  • Tothill, P
  • Nuki, G
Type
Published Article
Journal
The Journal of rheumatology
Publication Date
Oct 01, 1986
Volume
13
Issue
5
Pages
932–935
Identifiers
PMID: 3820204
Source
Medline
License
Unknown

Abstract

To assess bone mass in ankylosing spondylitis (AS) we have measured total body calcium, bone mineral content of the lumbar spine and metacarpal indices in groups of patients with AS. Mean total body calcium was reduced by 5.3% (p less than 0.05) in 20 patients compared with controls. The mean annual loss of bone, assessed over an 18 month period in 17 patients, was 2.9% (p less than 0.001). Compared to controls, bone mineral content was increased by 28% (p less than 0.05) in 8 male patients while metacarpal indices were normal in 18 male and female patients. The results of total body calcium measurements give support to the hypothesis of a minor increase in bone turnover in AS. The increased bone mineral content in the male patients may relate to syndesmophyte formation.

Report this publication

Statistics

Seen <100 times