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Bone marrow involvement in adult soft tissue sarcomas.

Authors
  • Bramwell, V H
  • Littley, M B
  • Chang, J
  • Crowther, D
Type
Published Article
Journal
European Journal of Cancer and Clinical Oncology
Publisher
Elsevier
Publication Date
Nov 01, 1982
Volume
18
Issue
11
Pages
1099–1106
Identifiers
PMID: 6297916
Source
Medline
License
Unknown

Abstract

Bone marrow biopsy was performed as part of the initial assessment in 74 patients with soft tissue sarcoma. Infiltration of the marrow by tumour was present in four cases, all from the group of 56 patients who had other evidence of metastatic disease, giving an overall incidence of 7%. The histological subtypes were pleomorphic rhabdomyosarcoma, angiosarcoma, synovial sarcoma and myxoid liposarcoma, of which the first three were high-grade tumours. Although it was not possible to determine whether response to chemotherapy was influenced by marrow involvement, haematological toxicity seemed excessive.

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