Bone cell proliferation on carbon nanotubes.
- Authors
- Type
- Published Article
- Journal
- Nano letters
- Publication Date
- Mar 01, 2006
- Volume
- 6
- Issue
- 3
- Pages
- 562–567
- Identifiers
- PMID: 16522063
- Source
- Medline
- License
- Unknown
Abstract
We explored the use of carbon nanotubes (CNTs) as suitable scaffold materials for osteoblast proliferation and bone formation. With the aim of controlling cell growth, osteosarcoma ROS 17/2.8 cells were cultured on chemically modified single-walled (SW) and multiwalled (MW) CNTs. CNTs carrying neutral electric charge sustained the highest cell growth and production of plate-shaped crystals. There was a dramatic change in cell morphology in osteoblasts cultured on MWNTs, which correlated with changes in plasma membrane functions.