Affordable Access

deepdyve-link
Publisher Website

Body mass, chronic heart failure, surgery and survival.

Authors
  • Clark, Andrew L1
  • Anker, Stefan D
Type
Published Article
Journal
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Publication Date
Mar 01, 2010
Volume
29
Issue
3
Pages
261–264
Identifiers
DOI: 10.1016/j.healun.2009.07.004
PMID: 19837608
Source
Medline
Language
English
License
Unknown

Abstract

Cardiac cachexia, associated with excessive activation of the sympathetic nervous system together with immune activation, is an important prognostic indicator in heart failure. Anecdotally, the prevalence of cardiac cachexia appears to be falling, perhaps due to the increased use of beta-blockers. However, chronic heart failure is so common that many patients continue to lose weight and continue to deteriorate to a point where transplantation or mechanical support is considered. The origin of cachexia remains elusive and further research is needed to explore the relation between weight, sympathetic activation, and the response to cardiac surgery or transplantation.

Report this publication

Statistics

Seen <100 times