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Blood mRNA biomarkers for detection of treatment response in acute pulmonary exacerbations of cystic fibrosis.

Authors
  • Nick, J A
  • Sanders, L A
  • Ickes, B
  • Briones, N J
  • Caceres, S M
  • Malcolm, K C
  • Brayshaw, S J
  • Chacon, C S
  • Barboa, C M
  • Jones, M C
  • St Clair, C
  • Taylor-Cousar, J L
  • Nichols, D P
  • Sagel, S D
  • Strand, M
  • Saavedra, M T
Type
Published Article
Journal
Thorax
Publisher
BMJ
Publication Date
Oct 01, 2013
Volume
68
Issue
10
Pages
929–937
Identifiers
DOI: 10.1136/thoraxjnl-2012-202278
PMID: 23783371
Source
Medline
Keywords
License
Unknown

Abstract

The addition of blood leucocyte gene expression to FEV(1) and CRP enhances specificity in predicting reduced pulmonary infection and may bolster the assessment of CF treatment outcomes.

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