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Blood bank conditions and RBCs: the progressive loss of metabolic modulation.

Authors
  • Messana, I
  • Ferroni, L
  • Misiti, F
  • Girelli, G
  • Pupella, S
  • Castagnola, M
  • Zappacosta, B
  • Giardina, B
Type
Published Article
Journal
Transfusion
Publication Date
Mar 01, 2000
Volume
40
Issue
3
Pages
353–360
Identifiers
PMID: 10738039
Source
Medline
License
Unknown

Abstract

RBCs stored in CPD-saline-adenine-glucose-mannitol do show a progressive loss of oxygen-dependent metabolic modulation, which is not restored after rejuvenation and which seems partly related to modifications in membrane proteins, mainly band 3.

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