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Bivalirudin inhibits periprocedural platelet function and tissue factor expression of human smooth muscle cells.

Authors
  • Pepke, Wojciech
  • Eisenreich, Andreas
  • Jaster, Markus
  • Ayral, Yunus
  • Bobbert, Peter
  • Mayer, Alexander
  • Schultheiss, Heinz-Peter
  • Rauch, Ursula
Type
Published Article
Journal
Cardiovascular therapeutics
Publication Date
Apr 01, 2013
Volume
31
Issue
2
Pages
115–123
Identifiers
DOI: 10.1111/j.1755-5922.2011.00305.x
PMID: 22212466
Source
Medline
License
Unknown

Abstract

Bivalirudin is better than UFH in reducing periprocedural platelet activation. Moreover, thrombin-induced TF expression is inhibited by bivalirudin. Thus, bivalirudin seems to be a better anticoagulant during PCI than UFH.

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