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Biomaterials in orthopaedics.

Authors
  • Navarro, M
  • Michiardi, A
  • Castaño, O
  • Planell, J A
Type
Published Article
Journal
Journal of The Royal Society Interface
Publisher
The Royal Society
Publication Date
Oct 06, 2008
Volume
5
Issue
27
Pages
1137–1158
Identifiers
DOI: 10.1098/rsif.2008.0151
PMID: 18667387
Source
Medline
License
Unknown

Abstract

At present, strong requirements in orthopaedics are still to be met, both in bone and joint substitution and in the repair and regeneration of bone defects. In this framework, tremendous advances in the biomaterials field have been made in the last 50 years where materials intended for biomedical purposes have evolved through three different generations, namely first generation (bioinert materials), second generation (bioactive and biodegradable materials) and third generation (materials designed to stimulate specific responses at the molecular level). In this review, the evolution of different metals, ceramics and polymers most commonly used in orthopaedic applications is discussed, as well as the different approaches used to fulfil the challenges faced by this medical field.

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