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Biomaterials from the sea: Future building blocks for biomedical applications.

Authors
  • Wan, Mei-Chen1
  • Qin, Wen1
  • Lei, Chen1
  • Li, Qi-Hong2
  • Meng, Meng1
  • Fang, Ming1
  • Song, Wen1
  • Chen, Ji-Hua1
  • Tay, Franklin3
  • Niu, Li-Na1, 4
  • 1 State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, PR China. , (China)
  • 2 Department of Stomatology, The Fifth Medical Centre, Chinese PLA General Hospital (Former 307th Hospital of the PLA), Dongda Street, Beijing, 100071, PR China. , (China)
  • 3 College of Graduate Studies, Augusta University, Augusta, GA, 30912, USA.
  • 4 The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, 453000, PR China. , (China)
Type
Published Article
Journal
Bioactive Materials
Publisher
KeAi Publishing
Publication Date
Dec 01, 2021
Volume
6
Issue
12
Pages
4255–4285
Identifiers
DOI: 10.1016/j.bioactmat.2021.04.028
PMID: 33997505
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Marine resources have tremendous potential for developing high-value biomaterials. The last decade has seen an increasing number of biomaterials that originate from marine organisms. This field is rapidly evolving. Marine biomaterials experience several periods of discovery and development ranging from coralline bone graft to polysaccharide-based biomaterials. The latter are represented by chitin and chitosan, marine-derived collagen, and composites of different organisms of marine origin. The diversity of marine natural products, their properties and applications are discussed thoroughly in the present review. These materials are easily available and possess excellent biocompatibility, biodegradability and potent bioactive characteristics. Important applications of marine biomaterials include medical applications, antimicrobial agents, drug delivery agents, anticoagulants, rehabilitation of diseases such as cardiovascular diseases, bone diseases and diabetes, as well as comestible, cosmetic and industrial applications. © 2021 The Authors.

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