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Biology, risk stratification, and therapy of pediatric acute leukemias: an update.

Authors
  • Pui, Ching-Hon
  • Carroll, William L
  • Meshinchi, Soheil
  • Arceci, Robert J
Type
Published Article
Journal
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology
Publication Date
Feb 10, 2011
Volume
29
Issue
5
Pages
551–565
Identifiers
DOI: 10.1200/JCO.2010.30.7405
PMID: 21220611
Source
Medline
License
Unknown

Abstract

The application of new high-throughput sequencing techniques to define the complete DNA sequence of leukemia and host normal cells and the development of new agents targeted to leukemogenic pathways promise to further improve outcome in the coming decade.

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