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Biological properties of synthetic glycoconjugate mimics of heparin comprising different molecular spacers.

Authors
  • Dreef-Tromp, C M
  • Basten, J E
  • Broekhoven, M A
  • van Dinther, T G
  • Petitou, M
  • van Boeckel, C A
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier
Publication Date
Aug 18, 1998
Volume
8
Issue
16
Pages
2081–2086
Identifiers
PMID: 9873490
Source
Medline
License
Unknown

Abstract

The in vitro antithrombotic activity of synthetic glycoconjugates I and II, comprising a flexible polyethylene glycol type and a rigid polyglucose type spacer, respectively, are compared to heparin.

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