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Biological perspectives. Aripiprazole: a third generation of antipsychotics begins?

Authors
  • Keltner, Norman L
  • Johnson, Vicki
Type
Published Article
Journal
Perspectives in psychiatric care
Publication Date
Jan 01, 2002
Volume
38
Issue
4
Pages
157–159
Identifiers
PMID: 12629954
Source
Medline
License
Unknown

Abstract

Schizophrenia places an incredible burden on patients, families, communities, and governments, therefore intense efforts to find therapeutic responses to this illness continue. The traditional antipsychotics were discovered by chance, the atypical antipsychotics were configured to preserve "what worked" while adding and eliminating important effects, and the next generation continues to evolve in an attempt to improve on previous generations. Aripiprazole is extoled as a new generation of antipsychotic drugs. Information to date suggests it is an effective antipsychotic with a remarkable side effect profile. We are hopeful this drug will provide a relief for the suffering associated with schizophrenia.

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