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[Biological markers of precancer of the large intestine].

Authors
  • Zagrebin, V M
Type
Published Article
Journal
Arkhiv patologii
Publication Date
Jan 01, 1995
Volume
57
Issue
4
Pages
89–92
Identifiers
PMID: 8526767
Source
Medline
License
Unknown

Abstract

Current views on focal defect in colorectal mucosa as a risk factor for development of tumours are presented. It is characterized by such phenotypical changes of the mucosa as cell proliferation activation, changes in ornithine decarboxylase activity and polyamine synthesis, changes in the expression of the blood group antigens and associated carbohydrate antigens as well as the development of small adenomas. All these changes may be biological markers of colonic precancer.

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