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Biological active macrocyclic diterpenoids from chinese drug "Fáng Féng Cáo"; II. Derivatives of ovatodiolids and their cytotoxity.

Authors
Type
Published Article
Journal
Planta medica
Publication Date
Issue
4
Pages
297–299
Identifiers
PMID: 17345312
Source
Medline
License
Unknown

Abstract

Isolated macrocyclic diterpenoids, ovatodiolide ( 1), 4, 5-epoxyovatodiolide ( 2), anisomelic acid ( 3), 4, 7-oxycycloanisomelic acid ( 4), and 4-methylene-5-oxoanisomelic acid ( 6), from the Chinese crude drug "Fáng Féng Cáordquo;, and the derivatives of the isolated compounds were tested for their growth inhibiting activities in culture of KB cell line. Besides, the effects of 1 on Ehrlich carcinoma in mice are reported.

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