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[Bioenergy metabolism in lymphocytes in ischemic heart disease].

Authors
  • Kuz'menko, D I
  • Balabanov, A V
  • Roman'ko, O Iu
  • Kanskaia, N V
  • Karpov, R S
Type
Published Article
Journal
Kardiologiia
Publication Date
Oct 01, 1987
Volume
27
Issue
10
Pages
59–62
Identifiers
PMID: 3695088
Source
Medline
License
Unknown

Abstract

Blood lymphocyte energy metabolism was assessed in coronary patients. Among intracellular adenine nucleotides, ATP was shown to be particularly prone to change, declining in proportion to the progress of the disease in all patients. ADP (1st functional class, or FC) and AMP (1st and 3d FC) declined less markedly. Atkinson's energy potential remained stable, although reduced significantly in patients of the 3d FC. Lymphocyte glycolytic activity was significantly lowered in patients of the 3d and 4th FC. Possible mechanisms of blood lymphocyte energy disorders, associated with coronary heart disease, are discussed.

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