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Biochemical measurements in Paget's disease of bone.

Authors
  • Walton, R J
  • Preston, C J
  • Bartlett, M
  • Smith, R
  • Russell, R G
Type
Published Article
Journal
European journal of clinical investigation
Publication Date
Feb 01, 1977
Volume
7
Issue
1
Pages
37–39
Identifiers
PMID: 402274
Source
Medline
License
Unknown

Abstract

In a group of eighty-three patients with untreated Paget's disease of bone, plasma alkaline phosphatase activity (AP), plasma non-protein-bound hydroxyproline concentration (PHP) and urinary excretion rate of total hydroxyproline (THP) were closely correlated with each other but not with fasting plasma concentrations of calcium or inorganic phosphate. Probit plots of AP and THP showed log-normal distributions overlapping the normal ranges.

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