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Binding of pyridine derivatives to cytochrome P-450.

Authors
  • Born, J L
  • Vaughn, D
Type
Published Article
Journal
Journal of pharmaceutical sciences
Publication Date
Jul 01, 1977
Volume
66
Issue
7
Pages
1046–1047
Identifiers
PMID: 886443
Source
Medline
License
Unknown

Abstract

The spectral binding constants, Ks, of pyridine, methylpyridine, and dimethylpyridines were determined. The Ks values of the compounds were discussed in terms of mechanisms of possible bonding to cytochrome P-450.

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