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The binding of adjuvant-active mycobacterial peptidoglycolipids and glycopeptides to mammalian membranes and their effect on artificial lipid bilayers.

Authors
Type
Published Article
Journal
Immunology
Publication Date
Volume
34
Issue
1
Pages
57–67
Identifiers
PMID: 414992
Source
Medline
License
Unknown

Abstract

The nature of the binding of adjuvant-active amphiphilic mycobacterial peptidoglycolipids and glycopeptides to mammalian plasma membranes was investigated together with their effect on the stability of artificial lipid bilayers. The importance of these interactions between mycobacterial components and membranes is discussed in relation to immunopotentiation, mitogenicity and tuberculous infection.

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