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Bilateral optic neuritis with spine demyelination associated with influenza A H1N1 infection.

Authors
  • Ambika, Selvakumar1
  • Lakshmi, Padma1
  • Veena Noronha, Olma2
  • 1 Department of Neuro-ophthalmology, Sankara Nethralaya- A unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India. , (India)
  • 2 Department of Radiology, Sankara Nethralaya- A unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India. , (India)
Type
Published Article
Journal
American Journal of Ophthalmology Case Reports
Publisher
Elsevier
Publication Date
Dec 01, 2020
Volume
20
Pages
101001–101001
Identifiers
DOI: 10.1016/j.ajoc.2020.101001
PMID: 33364518
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To report a rare case of optic neuritis with spine demyelination following H1N1 virus infection. A 66-year-old female presented with decreased vision in both eyes (left > right) following a recent episode of fever and flu. She was diagnosed as H1N1 infection confirmed by viral antigen analysis of throat swab. On examination, she had a profound vision drop in the left eye with optic disc edema. MRI brain and orbit revealed bilateral optic nerve and frontal dural thickening with a ring-enhancing lesion in the right frontal lobe. MRI spine showed long cord signals at T1-T7 suggestive of demyelination. The patient had a complete recovery of vision and visual fields after intravenous and oral steroids. Influenza A virus can manifest with a wide range of symptoms including flu-like illness to neurological complications. This case highlights optic neuritis as a presenting feature of H1N1 infection. © 2020 Published by Elsevier Inc.

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