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[Bilateral deafness and unilateral facial nerve palsy as presenting features of Wegener's granulomatosis : a case report].

Authors
Type
Published Article
Journal
HNO
Publication Date
Volume
58
Issue
5
Pages
480–483
Identifiers
DOI: 10.1007/s00106-009-2017-x
PMID: 20454885
Source
Medline

Abstract

A 72-year-old female patient presented with otitis of her left ear with inner ear depletion. Despite administration of intravenous antibiotics according to the resistogram and mastoidectomy the patient developed a similar pathological condition in the right ear and facial nerve palsy on the left side. Treatment with trimethoprim/sulfamethoxazole under the working diagnosis of a localised seronegative Wegener's granulomatosis was initiated without achieving remission. Cyclophosphamide pulse therapy in combination with high-dose methylprednisolone was initiated with rapid cure of the bilateral otitis. Sensorineural hearing loss and facial nerve palsy remained irreversible.

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