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Bidirectional associations between clinically relevant depression or anxiety and COPD: a systematic review and meta-analysis.

Authors
  • Atlantis, Evan1
  • Fahey, Paul2
  • Cochrane, Belinda3
  • Smith, Sheree4
  • 1 School of Nursing and Midwifery, Campbelltown Campus, NSW, Australia. Electronic address: [email protected] , (Australia)
  • 2 School of Science and Health, University of Western Sydney, Campbelltown Campus, NSW, Australia. , (Australia)
  • 3 School of Nursing and Midwifery, Campbelltown Campus, NSW, Australia; School of Medicine, University of Western Sydney, Campbelltown Campus, NSW, Australia; Campbelltown Hospital, Department of Medicine, SLHD/SWSLHD, Campbelltown, NSW, Australia. , (Australia)
  • 4 School of Nursing and Midwifery, Campbelltown Campus, NSW, Australia; Centre for Pharmacology and Therapeutics, Division of Experimental Medicine, Imperial College, South Kensington, London, England. , (Australia)
Type
Published Article
Journal
CHEST Journal
Publisher
Elsevier
Publication Date
September 2013
Volume
144
Issue
3
Pages
766–777
Identifiers
DOI: 10.1378/chest.12-1911
PMID: 23429910
Source
Medline
License
Unknown

Abstract

Depression and anxiety adversely affect prognosis in COPD, conferring an increased risk of exacerbation and possibly death. Conversely, COPD increases the risk of developing depression. These bidirectional associations suggest potential usefulness of screening for these disease combinations to direct timely therapeutic intervention.

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