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"BFA bodies": a subcompartment of the endoplasmic reticulum.

Authors
  • L Orci
  • A Perrelet
  • M Ravazzola
  • F T Wieland
  • R Schekman
  • J E Rothman
Publication Date
Dec 01, 1993
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

A specialized region of the endoplasmic reticulum--the BFA body--is defined by the site of accumulation of coatomer when nonclathrin coat protein (COP)-coated vesicle assembly is prevented by the drug brefeldin A (BFA). BFA bodies are formed by part smooth, part rough domains of endoplasmic reticulum that are cis to the classical transitional endoplasmic reticulum and to BFA-induced Golgi remnants.

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