Affordable Access

deepdyve-link
Publisher Website

Berries and anthocyanins: promising functional food ingredients with postprandial glycaemia-lowering effects.

Authors
  • Castro-Acosta, Monica L1
  • Lenihan-Geels, Georgia N1
  • Corpe, Christopher P1
  • Hall, Wendy L1
  • 1 Diabetes & Nutritional Sciences Division,King's College London,Franklin-Wilkins Building,150 Stamford Street,London SE1 9NH,UK.
Type
Published Article
Journal
Proceedings of The Nutrition Society
Publisher
Cambridge University Press
Publication Date
August 2016
Volume
75
Issue
3
Pages
342–355
Identifiers
DOI: 10.1017/S0029665116000240
PMID: 27170557
Source
Medline
Keywords
License
Unknown

Abstract

The prevalence of type 2 diabetes (T2D) is predicted to reach unprecedented levels in the next few decades. In addition to excess body weight, there may be other overlapping dietary drivers of impaired glucose homeostasis that are associated with an obesogenic diet, such as regular exposure to postprandial spikes in blood glucose arising from diets dominated by highly refined starches and added sugars. Strategies to reduce postprandial hyperglycaemia by optimising the functionality of foods would strengthen efforts to reduce the risk of T2D. Berry bioactives, including anthocyanins, are recognised for their inhibitory effects on carbohydrate digestion and glucose absorption. Regular consumption of berries has been associated with a reduction in the risk of T2D. This review aims to examine the evidence from in vitro, animal and human studies, showing that berries and berry anthocyanins may act in the gut to modulate postprandial glycaemia. Specifically, berry extracts and anthocyanins inhibit the activities of pancreatic α-amylase and α-glucosidase in the gut lumen, and interact with intestinal sugar transporters, sodium-dependent glucose transporter 1 and GLUT2, to reduce the rate of glucose uptake into the circulation. Growing evidence from randomised controlled trials suggests that berry extracts, purées and nectars acutely inhibit postprandial glycaemia and insulinaemia following oral carbohydrate loads. Evidence to date presents a sound basis for exploring the potential for using berries/berry extracts as an additional stratagem to weight loss, adherence to dietary guidelines and increasing physical exercise, for the prevention of T2D.

Report this publication

Statistics

Seen <100 times