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Benign Lymphoid Hyperplasia Presenting as Bilateral Scleral Nodules.

Authors
  • Cumba, Ricardo J
  • Vazquez-Botet, Rene
Type
Published Article
Journal
Case reports in ophthalmological medicine
Publication Date
Jan 01, 2015
Volume
2015
Pages
179609–179609
Identifiers
DOI: 10.1155/2015/179609
PMID: 26421203
Source
Medline
License
Unknown

Abstract

Purpose. To report a case of transient lymphoid hyperplasia presenting as bilateral nodular scleral mass in a young male patient. Design. Observational case report. Methods. Chart review. Causes of scleritis were considered and excluded based on detailed history, physical examination, and laboratory investigations. Results. Excisional biopsy of scleral lesions indicated lymphoid tissue. Immunohistochemical studies revealed a polyclonal population of T and B cells consistent with a benign reactive process. Conclusions. Chronic exposure of the ocular adnexa to many allergens and irritants may lead to activation of the inflammatory cascade. In severely allergic patients activation may be exponential and elicit an immune-mediated response resulting in a transient lymphoid reactive process.

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