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The beneficial effects of omega-3 and omega-6 essential fatty acid supplementation on red blood cell rheology.

Authors
Type
Published Article
Journal
Prostaglandins Leukotrienes and Essential Fatty Acids (PLEFA)
0952-3278
Publisher
Elsevier
Publication Date
Volume
61
Issue
1
Pages
13–17
Identifiers
PMID: 10477036
Source
Medline

Abstract

Twenty healthy, non-smoking subjects were enrolled into a study to investigate the effects of dietary supplementation with essential fatty acid (EFAs) on red blood cell rheology. Ten subjects were given 3 months dietary supplementation with long chain polyunsaturated EFAs containing omega-3 and omega-6 EFAs while 10 others were given placebo (sunflower oil). Venous sampling was performed at 0 and 12 weeks and red blood cell (RBC) aggregation and deformability measured by a filtration system. The results showed a reduction in RBC aggregation in the group given omega-3 and omega-6 EFAs but not in the placebo group. This may be related to changes in the RBC membrane and surface receptor characteristics. Such EFAs may be useful in Raynaud's phenomenon.

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