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Beneficial effects of N,N,N-trimethylsphingosine following ischemia and reperfusion in the isolated perfused rat heart.

Authors
  • Campbell, B
  • Shin, Y K
  • Scalia, R
  • Lefer, A M
Type
Published Article
Journal
Cardiovascular research
Publication Date
Aug 01, 1998
Volume
39
Issue
2
Pages
393–400
Identifiers
PMID: 9798524
Source
Medline
License
Unknown

Abstract

These results provide evidence that TMS is a potent and effective cardioprotective agent that inhibits leukocyte-endothelial cell interactions and preserves cardiac contractile function and coronary perfusion following myocardial ischemia and reperfusion.

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