Abstract The present study was undertaken to verify findings surrounding sex differences in color preferences, and to extend this realm of inquiry by looking for possible differences in color preferences associated with sexual orientation. Based on a large sample of North American college students, significant gender differences were found, with the main difference being a greater preference for shades of blue by males than by females. Females, on the other hand, tended to be more evenly divided than males between preferring both green and blue. Regarding sexual orientation, we found no significant differences between heterosexuals and homosexual/bisexuals of either gender. In other words, male and female homosexuals/bisexuals exhibited essentially the same configuration of color preferences as did their heterosexual counterparts.