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Beat-to-beat variations in activation recovery interval derived from the right ventricular electrogram can monitor arrhythmic risk under anesthetic and awake conditions in the canine chronic atrioventricular block model.

Authors
  • Wijers, Sofieke C1
  • Sprenkeler, David J1
  • Bossu, Alexandre1
  • Dunnink, Albert1
  • Beekman, Jet D M1
  • Varkevisser, Rosanne1
  • Aranda Hernández, Alfonso2
  • Meine, Mathias3
  • Vos, Marc A4
  • 1 Department of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, Yalelaan 50, 3584 CM, Utrecht, The Netherlands. , (Netherlands)
  • 2 Medtronic Bakken Research Center, Endepolsdomein 5, 6229 GW, Maastricht, The Netherlands. , (Netherlands)
  • 3 Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM, Utrecht, The Netherlands. , (Netherlands)
  • 4 Department of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, Yalelaan 50, 3584 CM, Utrecht, The Netherlands. Electronic address: [email protected] , (Netherlands)
Type
Published Article
Journal
Heart rhythm
Publication Date
Nov 13, 2017
Identifiers
DOI: 10.1016/j.hrthm.2017.11.011
PMID: 29146275
Source
Medline
Keywords
License
Unknown

Abstract

1) Both STVLVMAPD and STVRVMAPD increased before the first EB (1.29±0.58 to 3.05±1.70ms and 1.11±0.53 to 2.18±1.43ms respectively (p=0.001). 2a) STVRVARI increased from 2.82±0.33 to 3.77±0.69ms (p=0.001). 2b) Inducible subjects (4/8) showed an increase in STVRVARI from 2.65±0.55 to 3.45±0.33ms (in the first hour, p=0.02) and 4.20±1.33 (before the first EB, p=0.04) CONCLUSION: Behavior of STV from the right and the left ventricle is comparable. STVRVARI increases significantly before the occurrence of an arrhythmia, in awake and anaesthetized conditions. This can be integrated in devices to monitor arrhythmic risk.

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