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A New Member of the Spindle Orientation Club: Mammalian Intestinal Stem Cells

Authors
Journal
Cell Stem Cell
1934-5909
Publisher
Elsevier
Publication Date
Volume
6
Issue
2
Identifiers
DOI: 10.1016/j.stem.2010.01.009

Abstract

Mitotic spindles are stereotypically oriented in many stem cells, often leading to asymmetric outcomes of stem cell division. In this issue of Cell Stem Cell, Näthke and colleagues ( Quyn et al., 2010) report that mammalian intestinal stem cells exhibit an oriented spindle and asymmetry during division.

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