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Variation of acoustic attenuation coefficient slope estimates forin vivoliver

Authors
Journal
Ultrasound in Medicine & Biology
0301-5629
Publisher
Elsevier
Publication Date
Volume
8
Issue
4
Identifiers
DOI: 10.1016/s0301-5629(82)80008-2
Keywords
  • A-Scan Analysis
  • Attenuation
  • Diffuse Liver Disease
  • Spectral Estimation
  • Statistical Modeling
  • Tissue Characterization
Disciplines
  • Medicine
  • Musicology
  • Physics

Abstract

Abstract Characterization of diffuse alcoholic disease is being attempted by estimating the slope of the acoustic attenuation coefficient with frequency, a parameter denoted by β, from reflected ultrasound signals. The ultrasound signals reflected from within the body are distorted by the non-ideal properties of tissues. Two distorting mechanisms are considered: the propagation through nonhomogeneous media and the reflection from irregularly shaped interfaces. The mechanisms are modeled as random filters and their effect on estimating the value of β are considered. The variances of three β estimators are derived from the model. Clinical results on normals and patients with alcoholic liver disease are presented to verify the model.

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