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BCL2 gene abnormalities define distinct clinical subsets of follicular lymphoma.

Authors
  • Goodlad, J R
  • Batstone, P J
  • Hamilton, D A
  • Kernohan, N M
  • Levison, D A
  • White, J M
Type
Published Article
Journal
Histopathology
Publication Date
Sep 01, 2006
Volume
49
Issue
3
Pages
229–241
Identifiers
PMID: 16918969
Source
Medline
License
Unknown

Abstract

These results support the concept of a subtype of FL lacking t(14;18)(q32;q21), characterized by low-intensity bcl-2 expression, a predilection for extranodal sites, particularly the skin, and a more favourable outcome than t(14;18)(q32;q21)-positive FL.

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