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Imaging–Genetics Applications in Child Psychiatry

Authors
Journal
Journal of the American Academy of Child & Adolescent Psychiatry
0890-8567
Publisher
Elsevier
Publication Date
Volume
49
Issue
8
Identifiers
DOI: 10.1016/j.jaac.2009.12.022
Keywords
  • Imaging
  • Genetics
  • Anxiety
  • Children And Adolescents
Disciplines
  • Biology
  • Medicine

Abstract

Objective To place imaging–genetics research in the context of child psychiatry. Method A conceptual overview is provided, followed by discussion of specific research examples. Results Imaging–genetics research is described linking brain function to two specific genes, for the serotonin-reuptake-transporter protein and a monoamine oxidase enzyme. Work is then described on phenotype selection in imaging genetics. Conclusions Child psychiatry applications of imaging genetics are only beginning to emerge. The approach holds promise for advancing understandings of pathophysiology and therapeutics.

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