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Bartter's syndrome--treatment with potassium, spironolactone and ACE-inhibitor.

Authors
  • Clementsen, P
  • Høegholm, A
  • Hansen, C L
  • Damkjaer, M
  • Christensen, P
  • Giese, J
Type
Published Article
Journal
Journal of internal medicine
Publication Date
Feb 01, 1989
Volume
225
Issue
2
Pages
107–110
Identifiers
PMID: 2646391
Source
Medline
License
Unknown

Abstract

The treatment of Bartter's syndrome is fraught with difficulties, and there is no consensus concerning the pathogenetic mechanisms involved. Potassium depletion with hypokaliaemia is a dominant feature of the syndrome. In this case history, a 42-year-old woman suffering from Bartter's syndrome did not improve on several therapeutic trials. An impressive progress was noted, however, after intensive potassium repletion with subsequent potassium/spironolactone/ACE-inhibitor treatment. After 24 months her condition was unchanged with normal and stable Se-potassium concentration.

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