Affordable Access

Access to the full text

Bariatric Surgery-Associated Myelopathy

Authors
  • Asakly, Sewar
  • Magen-Rimon, Ramit
  • Ighbariya, Ahmad
  • Marjih-Shallufi, Miriam
  • Ben-Porat, Tair
  • Ravid, Sarit
  • Eran, Ayelet
  • Gepstein, Vardit
  • Hanna, Suhair
  • Weiss, Ram
Type
Published Article
Journal
Obesity Facts
Publisher
S. Karger AG
Publication Date
Jul 26, 2021
Volume
14
Issue
4
Pages
431–439
Identifiers
DOI: 10.1159/000515374
PMID: 34311464
Source
Karger
Keywords
Disciplines
  • Case Report
License
Green
External links

Abstract

Bariatric surgery is gaining acceptance as an efficient treatment modality for adults and adolescents with morbid obesity. The early postbariatric period has the potential to induce an immunomodulatory imbalance due to the development or worsening of nutritional deficiencies, changes in hormonal balance (specifically after sleeve gastrectomy), and a shift in the proinflammatory cytokine profile along with a major change in the gut microbiome and permeability. These changes may induce encephalomyelitic T cell activity, change neural barrier permeability, and induce gut dysbioisis, favoring a proinflammatory metabolic profile. Such changes, in genetically prone individuals or those with additional risk factors, may lead to the development of myelopathy, particularly MS. Key Message: Postbariatric myelopathy is rare but should be considered in bariatric patients with relevant complaints in the postoperative period.

Report this publication

Statistics

Seen <100 times