Affordable Access

Short and efficient diastereoselective synthesis of pyrrolidinone-containing dipeptide analogues

Authors
Publisher
Royal Society of Chemistry
Publication Date

Abstract

The pyrrolidine-2,4-diones have been identified as a convenient starting point for the synthesis of peptide analogues. Herein we describe an optimized two-step reductive amination procedure, which provides a small library of pyrrolidinone-containing dipeptide analogues in high yield and excellent diastereoselectivity.

There are no comments yet on this publication. Be the first to share your thoughts.