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Computer-assisted analysis of in vivo cytotoxic T cell responses

Authors
Journal
Journal of Immunological Methods
0022-1759
Publisher
Elsevier
Publication Date
Volume
64
Identifiers
DOI: 10.1016/0022-1759(83)90387-3
Keywords
  • Cytotoxicity Assay
  • Lytic Units
  • Individual Variability

Abstract

Abstract An approach has been devised for analysing data generated in the study of in vivo cytotoxic T cell responses. The method calculates the total number of lytic units generated in the peritoneal cavity, or in cultures of the lymph nodes draining the rear footpad, following antigenic stimulation. The assessment of group differences is facilitated, and the method lends itself to computerised and hence objective data analysis.

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