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Characterization of temperature-sensitive mutants of murine leukemia virus

Authors
Journal
Virology
0042-6822
Publisher
Elsevier
Publication Date
Volume
54
Issue
1
Identifiers
DOI: 10.1016/0042-6822(73)90113-x

Abstract

Abstract The isolation of temperature-sensitive (ts) mutants of the Rauscher strain of murine leukemia virus (MuLV) is described. These and a number of previously isolated ts mutants of the Kirsten strain of MuLV have been partially characterized and have been separated into three distinct classes based on the stage at which viral replication is blocked at the nonpermissive temperature.

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