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Relation between liver microsomal and mitochondrial lipids and plasma lipids in pregnant and nonpregnant rats

Authors
Journal
Journal of Ultrastructure Research
0022-5320
Publisher
Elsevier
Publication Date
Volume
41
Identifiers
DOI: 10.1016/s0022-5320(72)90077-9

Abstract

The phospholipids were studied in plasma and in liver subcellular fractions from nonpregnant and pregnant rats. The composition of the plasma phospholipids was changed during pregnancy. Similar phospholipid changes were observed in liver rough microsomal fractions in the pregnant rats, whereas the smooth microsomes and the mitochondria from the same livers displayed no significant phospholipid alterations. It is suggested that pregnancy induces changes in the phospholipid synthesis in the rough-surfaced endoplasmic reticulum of the liver cells which, at least to some degree, might be responsible for the plasma phospholipid alterations.

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