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Green fluorescent proteins are light-induced electron donors

Authors
Journal
Nature Chemical Biology
1552-4450
Publisher
Nature Publishing Group
Publication Date
Volume
5
Issue
7
Identifiers
DOI: 10.1038/nchembio.174
Keywords
  • Article
Disciplines
  • Biology
  • Chemistry
  • Medicine

Abstract

Proteins of the green fluorescent protein (GFP) family are well known due to their unique biochemistry and extensive use as in vivo markers. Here, we discovered a new feature of GFPs of diverse origins to act as the light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, this process accompanying with green-to-red GFP photoconversion can be observed in living cells without additional treatment.

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