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Multicomponent solution phase synthesis of dehydroamino acid derivatives based on the Passerini reaction

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
39
Issue
39
Identifiers
DOI: 10.1016/s0040-4039(98)01522-6

Abstract

Abstract We have synthesized a library of dehydroamino acid derivatives using a Passerini three component condensation reaction. A number of structurally diverse inputs were used, thus demonstrating a large tolerance of functionality for the key transformation.

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