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Didemnilactones A and B and neodidemnilactone three new fatty acid metabolites isolated from the tunicateDidemnum moseleyi(Herdman)

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
50
Issue
25
Identifiers
DOI: 10.1016/s0040-4020(01)90469-7
Disciplines
  • Chemistry

Abstract

Abstract Three new fatty acid metabolites didemnilactones A ( 1) and B ( 2) and neodidemnilactone ( 3) were isolated from the tunicate Didemnum moseleyi (Herdman). Their structures including absolute stereochemistry were established on the basis of spectral studies and chemical synthesis. Didemnilactones exhibited inhibitory activity against lipoxygenase and weak binding activity to leukotriene B 4 receptors.

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