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Changes in responsiveness of medial preoptic neurons to the microelectrophoresis of releasing hormones as a function of ovarian hormones

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
149
Issue
2
Identifiers
DOI: 10.1016/0006-8993(78)90495-x

Abstract

Abstract d-Ala 6, des-Gly 10-LRH ethylamide were generously provided by Drs. M. Götz and R. Deghenghi of Ayerst Research Laboratories, Montreal, Canada.Thyrotropin-releasing hormone was supplied by Drs. J. Dorn and J. Weinstein and Mr. C. Flanagan of Abbott Laboratories, North Chicago, Illinois, and Drs. Vale and Rivier of the Salk Institute at San Diego supplied the LRH analog peptides (1) d-Trp 6, Pro 9NHEt-LRH, agonist analog (LRH +), (2) d-Phe 2, d-Trp 2, dTrp 6-LRH, antagonist analog (LRH-) and (3) des-Pro 10-LRH inactive analog (LRH 0).

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