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Doubling in the use of thyroid hormone replacement therapy in Denmark: association to iodization of salt?

Authors
Publisher
Springer Netherlands
Publication Date
Keywords
  • Iodization Of Salt Is An Effective Strategy To Prevent Iodine Deficiency Disorders
  • Recent Studies
  • However
  • Indicate That Increasing The Iodine Intake In A Population May Give Rise To An Increased Incidence O
  • But The Association Has Not Been Fully Clarified
  • In Denmark
  • Iodization Of Salt Was Initiated In 1998 Because Of Mild-To-Moderate Iodine Deficiency
  • The Aim Of This Study Was To Evaluate The Effect Of The Raised Iodine Intake On The Nationwide Incid
  • Data On All Use Of Levothyroxine Was Extracted From The Register Of Medicinal Product Statistics Dur
  • Persons With Previous Thyroid Surgery Were Excluded
  • In The Studied Period 71
  • 565 Incident Users Were Identified
  • The Incidence Rate Increased 75% In The Moderately Iodine Deficient Region (72
  • 2 Incident Users/100
  • 000 Person-Years In 1997 To 126
  • 6 In 2008) And 87% In The Mildly Deficient Region (86
  • 9–162
  • 9)
  • When Stratified By Sex And Age-Group (00–39
  • 40–64
  • 65+) The Largest Relative Increase Was Seen Among Women In The Youngest Age-Group
  • Where More Than A Doubling Was Seen
  • The Mechanisms Behind The Increase May Be A Result Of Iodine-Induced Hypothyroidism
  • Although A Higher Diagnostic Activity With Regard To Thyroid Dysfunction And Intensified Treatment O
  • Our Findings Stress The Need For Caution When Initiating Iodine Fortification Programs To Keep The I
  • And The Need For Continuous Monitoring
Disciplines
  • Medicine

Abstract

Doubling in the use of thyroid hormone replacement therapy in Denmark: association to iodization of salt? - DTU Orbit (16/04/14) Doubling in the use of thyroid hormone replacement therapy in Denmark: association to iodization of salt? - DTU Orbit (16/04/14) Cerqueira, C., Knudsen, N., Ovesen, L., Laurberg, P., Perrild, H., Rasmussen, L. B., & Jørgensen, T. (2011). Doubling in the use of thyroid hormone replacement therapy in Denmark: association to iodization of salt?. European Journal of Epidemiology, 26(8), 629-635. 10.1007/s10654-011-9590-5

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