Affordable Access

Publisher Website

DNA microarray analysis as a tool to investigate the therapeutic mechanisms and drug development of Chinese medicinal herbs

Authors
Publisher
Elsevier B.V.
Volume
2
Issue
1
Identifiers
DOI: 10.1016/j.biomed.2012.02.002
Keywords
  • Dna Microarray
  • Gene Expression Profile
  • Traditional Chinese Medicine
Disciplines
  • Medicine

Abstract

Abstract Chinese herbal medicines have been used for the treatment of various diseases for centuries. Although several herbal formulas and herbal components have shown therapeutic potential, the active components and the molecular mechanisms mediating the effects of said formulas remain to be discovered. Microarray analysis has become a widely used tool for the generation of gene expression data on a genome-wide scale. This paper discusses the application of whole genome expression profiling as a tool to investigate the molecular mechanisms governing the therapeutic effects of traditional Chinese medicine. This review also highlights how data derived from DNA microarray analysis can be used to screen for drug targets of various herbal drugs, to predict the therapeutic potential of herbal drugs, to analyze the safety of drugs in the preclinical stage of drug development, and to establish a modern definition of traditional Chinese medicine.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

[The therapeutic effect of Chinese medicinal herbs...

on Zhonghua shi yan he lin chuang... Sep 30, 1999

Chinese medicinal herbs for mumps.

on The Cochrane database of syste... 2012

[Screening of anti-simian immunodeficiency virus (...

on Zhongguo Zhong xi yi jie he za... March 1993

Chinese medicinal herbs modulate mutagenesis, DNA...

on Mutation Research/Fundamental... Jun 01, 1992
More articles like this..