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Use of extracts ofPicralima nitidabark in the treatment of experimental trypanosomiasis: A preliminary study

Authors
Journal
Journal of Ethnopharmacology
0378-8741
Publisher
Elsevier
Publication Date
Volume
25
Issue
3
Identifiers
DOI: 10.1016/0378-8741(89)90032-9
Disciplines
  • Biology
  • Pharmacology

Abstract

Abstract The effect of a boiling water extract of Picralima nitida bark against trypanosomes ( T. brucei) in rats was compared with that of diminazene aceturate at 8 mg kg i.p. Results showed that the extract had a definite trypanocidal effect which was statistically comparable to that of diminazene aceturate. Further work is needed to identify the active pharmacological agent and to standardise the usage of the agent in practice.

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