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Comparison of intravenous pethidine infusion with ‘3 in 1’ lumbar plexus block after anterior cruciate ligament reconstruction

Elsevier B.V.
Publication Date
DOI: 10.1016/0968-0160(95)00005-a
  • Anterior Cruciate Ligament
  • Surgery
  • Analgesia


Abstract We studied 104 patients undergoing primary anterior cruciate ligament reconstruction who were prospectively randomized into receiving either an intravenous pethidine infusion or a continuous bupivicaine infusion to the lumbar plexus via the femoral sheath, for postoperative analgesia. No difference was found between the two methods in terms of their analgesic effect ( P > 0.1) and both were well tolerated by the patients with no serious complications. The incidence of nausea, vomiting and drowsiness was significantly higher in the pethidine infusion group ( P < 0.05) and remained higher despite the addition of an anti-emetic to the infusion ( P < 0.1). The mean pain scores and need for supplementary analgesia were higher in the patients in whom the mini-arthrotomy surgical technique was used when compared with the arthroscopically assisted technique ( P < 0.05).

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